
The same night, Harry learns that Janice is in labor, and he leaves Ruth to visit his wife at the hospital. Enraged, Harry coaxes Ruth into performing fellatio on him.

But Harry stays with Ruth until he learns she had a fling with his high school nemesis, Ronnie Harrison. The local Episcopal priest, Jack Eccles, tries to persuade Harry to reconcile with his wife. Meanwhile, Janice moves back in with her parents. Harry and Ruth begin a two-month affair and he moves into her apartment. That night, Harry has dinner with Tothero and two girls, one of whom, Ruth Leonard, is a part-time prostitute. After getting lost, he returns to his home town, but not wanting to return to his family, he instead visits his old basketball coach, Marty Tothero. Harry finds middle-class family life unsatisfying, and on the spur of the moment, leaves his family and drives south in an attempt to "escape". They live in Mount Judge, Pennsylvania, a suburb of Brewer, and have a two-year-old son named Nelson. He is married to Janice, who was a salesgirl at the store where he once worked, and who is now pregnant. Harry "Rabbit" Angstrom, formerly a high school basketball star, is now 26, and has a job selling a kitchen gadget named MagiPeeler. In these novels, Updike takes a comical and retrospective look at the relentless questing life of Rabbit against the background of the major events of the latter half of the 20th century. It spawned several sequels, including Rabbit Redux, Rabbit is Rich and Rabbit at Rest, as well as a related 2001 novella, Rabbit Remembered.

The novel depicts three months in the life of a 26-year-old former high school basketball player named Harry "Rabbit" Angstrom who is trapped in a loveless marriage and a boring sales job, and his attempts to escape the constraints of his life. Rabbit, Run is a 1960 novel by John Updike.
